The Hound Pits Pub
After getting off the boat, speak with Callista, who is waiting nearby. If you completed her optional task in the previous mission (Keep Curnow alive), she will give you a Bone Charm (1/1) . If Curnow dies, she’ll still chat with you, but you’ll get no reward. After that’s done, head over to the group of loyalists marked on the screen. Chat with them. At the end, choose the first option to rest.
After you wake up, make your way outside of the pub, pick some sleep bolts up from Piero and then head over and talk to Havelock. After a chat, you’ll be able to open the nearby hatch. Drop down. Make your way through the sewer, past the closed door and around the bend until you see the pair of weepers ahead. Hit them both with a sleeper dart to take them down without killing.
Now pull out your heart. You’ll see two new runes to pick up nearby. Grab them both and backtrack to the door we passed before. Cruise through the room here and climb the chain to return to ground level. Enter the pub and chat with the loyalists to get your next targets. Head over to Piero if you need any upgrades or ammo and then talk to Pendleton before cruising down to Samuel and hopping on the boat to begin the next mission.