After visiting the Hunter’s Dream, Iosefka will take over the room you began in and lock the doors. If you talk to the door she will give you a Iosefka’s Blood Vial , provided you do not have one already, up until you defeat Father Gascoigne.

After reaching Cathedral Ward:

Return to Iosefka and she will offer to harbor people, with a reward for each one that you send her way.

NPC Reward
Viola's Daughter Lead Elixir x2
Lonely Old Dear Numbing Mist x2
Arianna, Woman of Pleasure Numbing Mist x2
Narrow Minded Man Numbing Mist x2
Sister Adella Numbing Mist x2
Transformed Man Beast Blood Pellet x2

Note: Iosefka will experiment on any NPCs sent to her, eventually leading to their transformation into enemies. While this does not prevent you from getting their drops, this will prevent any characters who have a quest line attached to them.

Before defeating Rom, the Vacuous Spider:

Once you reach the Forbidden Woods you can enter Iosefka’s Clinic, where she can be found in a room upstairs. She will ask you to leave and if you continue forward she will become hostile, but if you leave and continue to send her victims after learning of her true intentions she’ll reward you with Blue Elixirs x3 for each.

After defeating Rom, the Vacuous Spider:

If you leave, or never visit, and return after defeating Rom, the Vacuous Spider you can safely head upstairs to easily kill her on a table.

Drops:

  • 3,200 Blood Echoes
  • Oedon Writhe Rune (Before defeating Rom, the Vacuous Spider)
  • One Third of Umbillical Cord (After defeating Rom, the Vacuous Spider)

Guide Information

  • Publisher
    Sony Computer Entertainment
  • Platforms
    PS4
  • Genre
    Action RPG
  • Guide Release
    1 May 2015
  • Last Updated
    29 October 2020
  • Guide Author
    Stephanie Barnes

Share this free guide:

Many travellers seek the city of Yharnam, famed for its Blood Ministration that many believe holds the key to cure their afflictions, but when an outsider arrives in town they find the city plagued with an endemic illness that has transformed most of its citizens into bestial creatures. Tasked with the job of hunting down the inflicted and finding something known as the Paleblood, the new Hunter finds themselves facing off against a group that wish to birth a god.

Join us as scour the darkness allies and defeat dangerous beasts while covering every aspect of this game including the following:

  • A detailed main walkthrough covering all events, detailed enemy strategies, and all 3 endings.
  • A checklist of all NPC events, with outcomes based on your decisions.
  • A complete trophy guide to help you reach that platinum trophy.
  • And much, much more!

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