Crisis Core Final Fantasy VII: Reunion has plenty of missable Trophies/Achievements, especially throughout the main story. The Of Significant Worth is one such Trophy/Achievement in Chapter 4.
Judged by Hojo to be a "SOLDIER member of significant worth" in the Fusion Chamber.
How to Answer All of Hojo’s Questions Correctly
Chapter 4 is just littered with Trophies/Achievements to earn, and this is another easy one to miss (like all of the Hojo related ones). You’ll have to progress through the Chapter until you return to the Shinra Building to protect Professor Hojo.
You’ll find yourself in the Fusion Chamber where you can interact with many different apparatus, most of which lead to a Trophy/Achievement. For the Of Significant Worth Trophy/Achievement, you’ll need to interact with the fusion chamber itself. At this point, Zack will get locked inside and Hojo will only let you out if you answer a series of questions correctly:
1. A SOLDIER operative like Sephiroth.
2. State-of-the-art science and technology.
3. A person unafraid to challenge Shinra
Answering all of them correctly and satisfying Hojo’s curiosity is enough to have him let Zack out of the fusion chamber and award you with the Of Significant Worth Trophy/Achievement. If you failed in answering any of the questions correctly, be sure to load up your Save (which should be in the same room as you are now).
Before speaking with Hojo to advance the story further, be sure to make sure you’ve completed the other tasks in the Fusion Chamber. You can also obtain the Precise Restoration Trophy/Achievement that requires you to successful count down to five seconds.
The Cell Raider Trophy/Achievement, on the other hand, is a lengthier one that requires you to successfully steal cell keys from the hound enemies and use it to open every cell and loot every chest before the time runs out. You can learn more about these Trophy/Achievements on their respective pages.